Cervical Esophageal Adenocarcinoma Originating from the Esophageal Gland

Abstract We describe a rare case of cervical esophageal adenocarcinoma originating from the esophageal gland. A 63-year-old man underwent endoscopic screening during a medical checkup, during which a type 2 tumor was incidentally detected in the cervical esophagus, which was confirmed as adenocarcinoma on biopsy. Endoscopic ultrasonography indicated that the tumor had invaded the muscularis propria layer. Computed tomography and F-fluorodeoxyglucose positron emission tomography imaging revealed neither lymphadenopathy nor distant metastasis. He was clinically diagnosed with T2N0M0, Stage II disease. He preoperatively received 2 courses of chemotherapy consisting of cisplatin (90mg/m) on day 1 and 5-fluorouracil (900mg/m) on days 1‒5. Esophagectomy with lymph node dissection was performed. Histopathological diagnosis showed well-differentiated tubular adenocarcinoma that probably originated from the ducts of the esophageal glands. The final diagnosis was T1bN0M0, Stage I disease. The postoperative course was uneventful. He was healthy without any recurrence 27 months after the surgery.